By American Academy of Ophthalmology, Robert H. Rosa Jr. MD
Part four offers fabrics in elements: half I, Ophthalmic Pathology; and half II, Intraocular Tumors: scientific elements. half I makes use of a hierarchy that strikes from normal to precise to assist derive a differential analysis for a particular tissue. half II is a compilation of chosen scientific features of value to the final ophthalmologist. Following half II are the yankee Joint Committee on melanoma 2010 staging varieties for ocular and adnexal tumors.
Upon finishing touch of part four, readers may be capable to:
Describe a established method of figuring out significant ocular stipulations according to a hierarchical framework of topography, disorder procedure, normal analysis and differential diagnosis
Summarize the stairs in dealing with ocular specimens for pathologic learn, together with acquiring, dissecting, processing, and marking tissues
Identify these ophthalmic lesions that point out systemic ailment and are in all likelihood lifestyles threatening
Read or Download 2014-2015 Basic and Clinical Science Course (BCSC): Section 4: Ophthalmic Pathology and Intraocular Tumors PDF
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Extra resources for 2014-2015 Basic and Clinical Science Course (BCSC): Section 4: Ophthalmic Pathology and Intraocular Tumors
The sclera becomes massively thickened, particularly posteriorly. 1 i e i t f t B Phthisis bulbi. A, Gross photograph showing globe with irregular contour, cataractous lens with calcification (asterisk), cyclitic membrane with adherent retina (arrowheads), organized ciliochoroidal effusion (open arrows), and bone formation (between green arrows). B, Photomicrograph demonstrating histopathologic correlation with gross photograph in A. Figure 2-11 (Courtesy of Robert H. ---- ------------- -· ,. CHAPTER .
As the excited fluorochrome returns to its resting energy level, a specific wavelength of light is emitted (c), which is sorted by wavelength (d) and re ceived by a photodetector (e). This signal is then converted to electronic impulses, which are in turn analyzed by computer software. /Courtesy of Patricia Chevez-Barrios, M D.! Figure 4-3 (a). CHAPTER 4: Special Procedures • 37 ,, ,- e. l ) ctronic impulses, which are in turn analyzed by computer software. The results may be ~~aged by a m~ticolore~ d~t-plo_t histogram (Fig 4~4).
The ophthalmic surgeon is responsible for appropriately obtaining and submitting tissue for evaluation and consulting with the ophthalmic pathologist. See Table 4-1 for a checklist of important considerations when submitting tissue for pathologic consultation. lmmunohistochemistry Pathologists making a diagnosis take advantage of the property that a given cell can express specific antigens. The immunohistochemical stains commonly used in ophthalmic pathology work because a primary antibody binds to a specific antigen in or on a cell, and because that antibody is linked to a chromogen, usually through a secondary antibody (Fig 4-1).