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Extra info for Advances in Psychology Research Volume 44
Thus, they have had to deal with: (a) scientific complexities such as facilitating adherence to a psychologicallyoriented treatment of the mood disorder even though patients expected to be treated for a physical illness; and (b) attracting the resources needed for costly randomized psychotherapy trials in the absence of generous fiscal support resembling that provided by the drug industry for pharmacotherapy research.
The data were also presented coming from both experimental and clinical studies showing favorable effects of lithium on many parameters of cellular and humoral immunity. Some evidence was also provided that lithium may alleviate the immune-endocrine component concomitant to an acute affective episode, such as acute phase reaction, cytokine secretion and hyperactivation of hypothalamic-pituitary-adrenal axis. It was speculated that the antiviral and immunomodulatory properties of lithium may Fifty-Five Years of Lithium Therapy in Contemporary Psychiatry 27 contribute to psychotropic actions of this drug, especially prevention of recurrences in affective illness and perhaps also to decreased mortality of lithium-treated patients .
Johnson (Australia), B. Müller-Oerlinghausen (Germany), P. J. Perry (USA), P. Plenge (Denmark), J. Rybakowski (Poland), M. Schou (Denmark), K. Thomsen (Denmark), S. P. Wehr (USA), Yang Shan Ming (China). The journal was published quarterly by Churchill Livingstone. Paradoxically, the advent of “Lithium” as a journal coincided with relative general decrease in the interest of lithium occurring in the fifth decade of lithium therapy. The journal existed for five years: 1990-1994. Several factors which took place in the fifth decade of lithium therapy contributed to the decrease of its importance what also resulted in a slower pace of lithium research.